Drug Candidates

2 candidates mapped to SDH-deficient disease pathways

All (15)established (4)clinical trial (2)preclinical (6)theoretical (3)
Belzutifan

Welireg

established

HIF-2α inhibitor

Hif Pseudohypoxia
Evidence Score
82
FDA Approved
Dichloroacetate (DCA)
preclinical

Pyruvate dehydrogenase kinase inhibitor

Hif PseudohypoxiaOxidative Stress Ros
Evidence Score
35